{"id":7974082412832,"title":"ALAmax","handle":"alamax-xymogen","description":"\u003cul\u003e\n\u003cli\u003eProvides antioxidants for the maintenance of good health\u003c\/li\u003e\n\u003cli\u003eHelps promote healthy glucose metabolism\u003c\/li\u003e\n\u003cli\u003eHelps metabolize fats, carbohydrates and proteins\u003c\/li\u003e\n\u003cli\u003eHelps prevent biotin deficiency\u003c\/li\u003e\n\u003c\/ul\u003e\n[TABS]\n\u003ch5\u003eDescription\u003cbr\u003e\u003c\/h5\u003e\n\u003cp\u003eAlpha-lipoic acid (ALA) is a water- and fat-soluble eight-carbon disulfide compound that is synthesized in small amounts in the liver and other tissues. Oral supplementation readily crosses the blood-brain barrier after being absorbed in the small intestine, enters the portal vein and is distributed via the systemic circulation. Once in tissues, ALA is found inside and outside of cells, including inside mitochondria where it naturally functions as a coenzyme for the oxidation of pyruvate, alpha-ketoglutarate, and branched-chain amino acids.\u003c\/p\u003e\n\u003cp\u003eResearchers have recently identified mechanisms of action of lipoic acid related to the maintenance of metabolic health. It has a direct binding site at the tyrosine kinase domain of the insulin receptor. ALA appears to modulate 5'-AMP-activated protein kinase and PPAR-regulated genes, activate PPAR-alpha and PPAR-gamma, and support PPAR-gamma mRNA and protein expression in cardiac tissue and aortic smooth muscle.\u003c\/p\u003e\n\u003cp\u003eControlled release technology supports the efficacy of alpha-lipoic acid in helping to maintain blood glucose levels already in the normal range. Data from a 12-week clinical study indicate that supplementation with ALAmax CRTM (1200 mg per day, divided doses) can support healthy levels of C-peptide.\u003c\/p\u003e\n\u003cp\u003eAlpha-lipoic acid effectively neutralizes a variety of free radicals, including oxygen radicals and ionized metals. This action is particularly beneficial for people who have higher levels of oxidative stress. Alpha-lipoic acid regenerates vitamins C and E, increases glutathione levels in tissues, and helps maintain the proper ratio of reduced to oxidized coenzyme Q10 in the mitochondria. In addition, alpha-lipoic acid can help the body rid itself of heavy metals.\u003c\/p\u003e\n\u003cp\u003eHealthy endothelium-mediated vasodilation is accepted as a surrogate marker for cardiovascular health and may be affected by the synthesis, bioavailability, or action of nitric oxide (NO). Increased oxidative stress appears to play an important role in the neutralization or inactivation of NO. The antioxidant properties of ALA, as well as its demonstrated safety and potency, qualify it as a prime candidate for evaluation of its ability to support healthy endothelial function.\u003c\/p\u003e\n\u003cp\u003eThe ability of alpha-lipoic acid to improve energy metabolism and reduce oxidative stress alludes to its ability to support healthy mitochondrial function with age.\u003c\/p\u003e\n\u003cp\u003eBiotin was added because chronic administration of lipoic acid reduces pyruvate carboxylase and beta-methylcrotonyl-CoA carboxylase activities in vivo by competing with biotin.\u003c\/p\u003e\n\u003ch5\u003eDosage\u003cbr\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e\u003cspan\u003e \u003cb\u003eAdults: \u003c\/b\u003eTake 1 tablet daily or as directed by your healthcare professional. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003eNutritional informations\u003cbr\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cstrong\u003eMedicinal ingredients (per tablet):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003eBiotin ...... 450 mcg\u003cbr\u003eDL-alpha-lipoic acid\u0026nbsp;...... 600 mg\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eNon-medicinal ingredients: \u003c\/b\u003eHypromellose, magnesium stearate, microcrystalline cellulose, hydroxypropyl cellulose, dibasic calcium phosphate, silica, medium chain triglycerides. \u003c\/span\u003e\u003c\/p\u003e\n[\/TABS]","published_at":"2022-10-25T18:30:37-04:00","created_at":"2022-10-25T18:30:40-04:00","vendor":"Xymogen","type":"","tags":["Comprimés","Glycémie","Mélange \/ Synergie","Rabais_40%","SYSTÈME CARDIOVASCULAIRE","SYSTÈME ENDOCRINIEN"],"price":4739,"price_min":4739,"price_max":4739,"available":true,"price_varies":false,"compare_at_price":7899,"compare_at_price_min":7899,"compare_at_price_max":7899,"compare_at_price_varies":false,"variants":[{"id":43673525518624,"title":"60 tablets","option1":"60 tablets","option2":null,"option3":null,"sku":"alamax-xymogen-60-comprimés","requires_shipping":true,"taxable":true,"featured_image":{"id":41853198467360,"product_id":7974082412832,"position":1,"created_at":"2023-06-30T09:53:44-04:00","updated_at":"2023-06-30T09:53:44-04:00","alt":null,"width":555,"height":741,"src":"\/\/unytii.com\/cdn\/shop\/products\/EnergiePLP-Produits_XymogenCanada_0000s_0082_ALAmax_83490a76-b603-4588-b897-9678e920eb2a.jpg?v=1688133224","variant_ids":[43673525518624]},"available":true,"name":"ALAmax - 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Oral supplementation readily crosses the blood-brain barrier after being absorbed in the small intestine, enters the portal vein and is distributed via the systemic circulation. Once in tissues, ALA is found inside and outside of cells, including inside mitochondria where it naturally functions as a coenzyme for the oxidation of pyruvate, alpha-ketoglutarate, and branched-chain amino acids.\u003c\/p\u003e\n\u003cp\u003eResearchers have recently identified mechanisms of action of lipoic acid related to the maintenance of metabolic health. It has a direct binding site at the tyrosine kinase domain of the insulin receptor. ALA appears to modulate 5'-AMP-activated protein kinase and PPAR-regulated genes, activate PPAR-alpha and PPAR-gamma, and support PPAR-gamma mRNA and protein expression in cardiac tissue and aortic smooth muscle.\u003c\/p\u003e\n\u003cp\u003eControlled release technology supports the efficacy of alpha-lipoic acid in helping to maintain blood glucose levels already in the normal range. Data from a 12-week clinical study indicate that supplementation with ALAmax CRTM (1200 mg per day, divided doses) can support healthy levels of C-peptide.\u003c\/p\u003e\n\u003cp\u003eAlpha-lipoic acid effectively neutralizes a variety of free radicals, including oxygen radicals and ionized metals. This action is particularly beneficial for people who have higher levels of oxidative stress. Alpha-lipoic acid regenerates vitamins C and E, increases glutathione levels in tissues, and helps maintain the proper ratio of reduced to oxidized coenzyme Q10 in the mitochondria. In addition, alpha-lipoic acid can help the body rid itself of heavy metals.\u003c\/p\u003e\n\u003cp\u003eHealthy endothelium-mediated vasodilation is accepted as a surrogate marker for cardiovascular health and may be affected by the synthesis, bioavailability, or action of nitric oxide (NO). Increased oxidative stress appears to play an important role in the neutralization or inactivation of NO. The antioxidant properties of ALA, as well as its demonstrated safety and potency, qualify it as a prime candidate for evaluation of its ability to support healthy endothelial function.\u003c\/p\u003e\n\u003cp\u003eThe ability of alpha-lipoic acid to improve energy metabolism and reduce oxidative stress alludes to its ability to support healthy mitochondrial function with age.\u003c\/p\u003e\n\u003cp\u003eBiotin was added because chronic administration of lipoic acid reduces pyruvate carboxylase and beta-methylcrotonyl-CoA carboxylase activities in vivo by competing with biotin.\u003c\/p\u003e\n\u003ch5\u003eDosage\u003cbr\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e\u003cspan\u003e \u003cb\u003eAdults: \u003c\/b\u003eTake 1 tablet daily or as directed by your healthcare professional. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003eNutritional informations\u003cbr\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cstrong\u003eMedicinal ingredients (per tablet):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003eBiotin ...... 450 mcg\u003cbr\u003eDL-alpha-lipoic acid\u0026nbsp;...... 600 mg\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eNon-medicinal ingredients: \u003c\/b\u003eHypromellose, magnesium stearate, microcrystalline cellulose, hydroxypropyl cellulose, dibasic calcium phosphate, silica, medium chain triglycerides. \u003c\/span\u003e\u003c\/p\u003e\n[\/TABS]"}