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In an unstressed state, Nrf2 is anchored in the cytoplasm by its specific inhibitor Keap1 (kelch-like ECH-associated protein 1). Keap1 functions as a sensor for oxidants and electrophilic xenobiotics. In the presence of any of these substances, Keap1 gives up its inhibition of Nrf2. This action stabilizes Nrf2, allowing it to accumulate in the nucleus and bind to the antioxidant response element (ARE) located in the enhancers of its target genes. Under this circumstance, Nrf2 then upregulates a variety of antioxidant enzymes and detoxifying proteins.\u003c\/p\u003e\n\u003ch5\u003eDosage\u003cbr\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eAdults:\u003c\/b\u003e Take 1 capsule daily with food or as recommended by a healthcare practitioner.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003eNutritional informations\u003cbr\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cstrong\u003eMedicinal ingredients (per capsule):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003eGlucoraphanin (from broccoli extract)(Brassica oleracea italica)(seed)(truebroc®)\u0026nbsp;...... 30 mg\u003cbr\u003eGreen tea (Camellia sinensis, Leaf) ...... 200 mg (60% Catechins, 30% Epigallocatechin 3-gallate, 6% Caffeine)\u003cbr\u003eCurcumin (Curcuma longa (rhizome) - root)\u0026nbsp;...... 130 mg\u003cbr\u003ePterostilbene ...... 50 mg\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eNon-medicinal ingredients:\u003c\/b\u003e Hypromellose, magnesium stearate, stearic acid, silica.\u003c\/span\u003e\u003c\/p\u003e\n[\/TABS]"}

Nrf2 Gene-R8

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Nrf2 Gene-R8

Manufacturer : Xymogen
NPN: 80100604

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Summary

  • Source of antioxidants for the maintenance of good health.

Nrf2 (NF-E2-related factor 2), a transcription factor in humans that is encoded by the NFE2L2 gene, regulates the expression of a set of antioxidant and detoxifying genes. In an unstressed state, Nrf2 is anchored in the cytoplasm by its specific inhibitor Keap1 (kelch-like ECH-associated protein 1). Keap1 functions as a sensor for oxidants and electrophilic xenobiotics. In the presence of any of these substances, Keap1 gives up its inhibition of Nrf2. This action stabilizes Nrf2, allowing it to accumulate in the nucleus and bind to the antioxidant response element (ARE) located in the enhancers of its target genes. Under this circumstance, Nrf2 then upregulates a variety of antioxidant enzymes and detoxifying proteins.

Adults: Take 1 capsule daily with food or as recommended by a healthcare practitioner.

Medicinal ingredients (per capsule):

Glucoraphanin (from broccoli extract)(Brassica oleracea italica)(seed)(truebroc®) ...... 30 mg
Green tea (Camellia sinensis, Leaf) ...... 200 mg (60% Catechins, 30% Epigallocatechin 3-gallate, 6% Caffeine)
Curcumin (Curcuma longa (rhizome) - root) ...... 130 mg
Pterostilbene ...... 50 mg

Non-medicinal ingredients: Hypromellose, magnesium stearate, stearic acid, silica.

Do you have any questions?

Do you have any questions?

You can reach our team of experts by phone Monday through Friday from 10am to 5pm. We will be able to help you choose the right product for you.

+1 877-575-0616

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courteous and personalized

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anywhere in Canada

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Nrf2 Gene-R8

$81.99